低聚果糖诱导的奶牛急性蹄叶炎血液糖脂代谢的研究

doi:10.11843/j.issn.0366-6964.2019.11.018

Abstract

Abstract: In order to investigate the changes in serum biochemical parameters during the course of acute laminitis in dairy cows, 12 healthy Chinese Holstein cows were used in this study. The experimental group was treated with 17 g·kg^-1 body weight of oligofructose which was dissolved in 20 mL·kg^-1 body weight of water, and the control group was given the same amount of water. Blood samples were collected at several fixed time points from 3 days before administration to 3 days after administration to detect blood glucose, insulin (INS), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol (CHOL), leptin (LEP), adiponectin (ADP) and CD36. Results were as follows:After the administration, the cows developed symptoms such as diarrhea, lameness, increased hoof temperature, hyperthyroidism of the finger (toe), and slowing of rumen peristalsis. The blood glucose of the experimental group began to rise significantly at 6 h after administration and lasted untill 18 h, and the INS content decreased significantly at 6-12 and 36-48 h. CHOL showed a significant downward trend from 6 to 72 h after administration. TG and HDL-C showed a significant downward trend at 12 h. LDL-C began to decrease significantly at 36 h compared with the control group. LEP was increased significantly at 12, 18 and 36 h. Blood glucose and INS levels, as well as serum lipid levels, are significant and may be the diagnostic criteria for acute laminitis.

CLC Number:

S856

LI Yuepeng, DING Jiafeng, ZHANG Xianhao, LI Shuaichen, ZHANG Jiantao, WANG Hongbin. Metabolism of Glucose and Lipid in the Blood of Acute Laminitis in Dairy Cows Induced by Oligofructose[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(11): 2333-2338.

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Metabolism of Glucose and Lipid in the Blood of Acute Laminitis in Dairy Cows Induced by Oligofructose

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